Great plate count anomaly

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There is a huge diversity of microbes on earth but only a few species can be cultivated.

Pure culture techniques with the use of conventional media is routine. But the pure culture is an artificial situation which hinders many microbes from growing. Most microbes remain uncultured as revealed by molecular techniques. A cultural approach can, on the other hand, give information that molecular techniques can't give.

SEE also Culture, Cultivation

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